Adelaide, Australia – A polyurethane-based solution for skin grafts has been developed by a team at the Royal Adelaide Hospital.
Burns surgeon John Greenwood won South Australia's 2016 Australian of the Year Award for the innovation.
The innovation is a biodegradable temporising matrix (BTM), which the team's study describes as a “dermal scaffold” for human skin.
BTM involves an expandable polyurethane seal which is inserted into a wound. Greenwood is now exploring the potential for growing large volumes of skin using a bioreactor.
A study of ten burns patients, which was published in 2015, reported that in all cases BTM was “tolerated without symptom or sign of adverse reaction” and “implantation was straightforward”.
PU was chosen partly due to its cost effectiveness compared with traditional skin graft methods.
The technology used to develop BTM Melbourne, Australia-based Polynovo's open cell foam.